With Neve Campbell, Courteney Cox, David Arquette, Jada Pinkett Smith. Mickey Altieri is the secondary antagonist of the 1997 horror film, Scream 2. Mickey : You should really deal with your trust issues Sid: I mean, poor Derek. Directed by Wes Craven. He's completely innocent and such a nice boy too. He was one of Sidney Prescott's best friends at college and was was obsessed with movies and often filmed whatever was going on. Scream 2 (1997) Timothy Olyphant as Mickey. Two years after the first series of murders, as Sydney acclimates to college life, someone donning the Ghostface costume begins a new string of killings.